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Showing posts from January, 2023

Immunomodulators & their side effects periodic runs (CAPS)

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Immunomodulators are medicines that can support the vulnerable function by modifying, in a salutary way, the vulnerable system’s response to a trouble. They're used to treat conditions similar as multiple sclerosis (wherein the jitters don't serve duly), heritable angioedema (HAE-an vulnerable complaint passed down through families), rheumatoid arthritis (a condition in which the body attacks its own joints causing pain, swelling, and loss of function), and Cryopyrin- associated periodic runs (CAPS). Although they don't cure multiple sclerosis and HAE, they may reduce the occurrences of symptoms in cases with relapsing- remitting multiple sclerosis (course of complaint where symptoms flare up from time to time) and decelerate down the progression of the complaint. The vulnerable system is a complex network of cells, apkins, and organs. Together, they help the body fight infections and conditions. When the vulnerable system recognizes an antigen (a substance that the body id

Asymptomatic and infections to life-threatening disease

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Immunology is the study of the immune system and is a very important branch of the medical and biological sciences. The immune system protects us from infection through various lines of defence. SARS-CoV-2 infections display tremendous interindividual variability, ranging from asymptomatic infections to life-threatening disease.  Inborn errors of, and autoantibodies directed against, type I interferons (IFNs) account for about 20% of critical COVID-19 cases among SARS-CoV-2-infected individuals. By contrast, the genetic and immunological determinants of resistance to infection per se remain unknown. Following the discovery that autosomal recessive deficiency in the DARC chemokine receptor confers resistance to Plasmodium vivax, autosomal recessive deficiencies of chemokine receptor 5 (CCR5) and the enzyme FUT2 were shown to underlie resistance to HIV-1 and noroviruses, respectively. Along the same lines, we propose a strategy for identifying, recruiting, and genetically analyzing indiv